- Review Article
- Allergy
- Eosinophils and childhood asthma
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Bong Seok Choi
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Clin Exp Pediatr. 2021;64(2):60-67. Published online January 6, 2021
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•In allergic eosinophilic asthma, eosinophils act as important effector cells and antigen-presenting cells, while in nonallergic eosinophilic asthma, type 2 innate lymphoid cells play an important role in eosinophil activation.
•Sputum eosinophil counts can be helpful for evaluating allergic airway inflammation in asthma.
• Anti-interleukin-5 has broadened the scope of asthma treatment. |
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- Original Article
- Nephrology (Genitourinary)
- Renal involvement in children and adolescents with inflammatory bowel disease
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Hea Min Jang, Hee Sun Baek, Jung-Eun Kim, Ju Young Kim, Yeon Hee Lee, Hee Yeon Cho, Yon Ho Choe, Ben Kang, Byung-Ho Choe, Bong Seok Choi, Min Hyun Cho
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Clin Exp Pediatr. 2018;61(10):327-331. Published online September 12, 2018
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Purpose: The incidence of inflammatory bowel disease (IBD) is rapidly increasing, and several reports have described the renal complications of IBD. We sought to evaluate the clinical manifestations of renal complications in children with IBD in order to enable early detection and prompt treatment of the complications.
Methods: We retrospectively reviewed the medical records of 456 children and adolescents aged <20... |
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- Case Report
- Nephrology (Genitourinary)
- Deficiency of antidiuretic hormone: a rare cause of massive polyuria after kidney transplantation
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Kyung Mi Jang, Young Soo Sohn, Young Ju Hwang, Bong Seok Choi, Min Hyun Cho
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Clin Exp Pediatr. 2016;59(4):202-204. Published online April 30, 2016
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A 15-year-old boy, who was diagnosed with Alport syndrome and end-stage renal disease, received a renal transplant from a living-related donor. On postoperative day 1, his daily urine output was 10,000 mL despite normal graft function. His laboratory findings including urine, serum osmolality, and antidiuretic hormone levels showed signs similar to central diabetes insipidus, so he was administered desmopressin acetate... |
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- Original Article
- Vitamin D serum levels in children with allergic and vasomotor rhinitis
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Seung Jin Lee, Bong Hwa Kang, Bong Seok Choi
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Clin Exp Pediatr. 2015;58(9):325-329. Published online September 21, 2015
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Purpose In addition to regulating calcium and phosphorus homeostasis and bone metabolism, vitamin D is known as an immune modulator. Recently, there has been increased worldwide interest in the association between low levels of vitamin D and allergic diseases. The purpose of this study was to assess the relationship between serum vitamin D levels and allergic/vasomotor rhinitis (AR/VR) in children. MethodsThis study... |
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- Increased B cell-activating factor (BAFF) level in the sputum of children with asthma
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Hye Mi Jee, Bong Seok Choi, Kyung Won Kim, Myung Hyun Sohn, Man Yong Han, Kyu-Earn Kim
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Clin Exp Pediatr. 2010;53(8):795-800. Published online August 31, 2010
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Purpose B cell-activating factor (BAFF) is a tumor-necrosis factor (TNF) superfamily member best known for its role in the survival and maturation of B cells. BAFF activity is observed in naïve cells as well as in effector/memory T cells. We aimed to explore whether BAFF in sputum is expressed at elevated levels in asthmatic airways and associated with eosinophilic inflammation, pulmonary... |
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- Case Report
- A Case of Congenital Hepatic Fibrosis Accompanied by
Renal Tubular Ectasia, Caroli Syndrome and Choledochal Cyst
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Bong Seok Choi, Sang Nam Bae, Yong Tak Im, Jae Hong Park, Chang Hoon Lee, Jun Woo Lee
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Clin Exp Pediatr. 2002;45(7):923-927. Published online July 15, 2002
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Congenital hepatic fibrosis is a relatively rare disease, characterized by bile ductular proliferation and prominent fibrosis in the portal area of liver resulting in portal hypertension. It is frequently associated with other abnormalities such as polycystic kidney, Caroli syndrome, cystic dysplasia of pancreas, intestinal lymphangiectasia, pulmonary emphysema, hemangioma, and cleft palate. We report here a case of congenital hepatic fibrosis... |
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- A Case Report of Congenital Hyperekplexia in Twin
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Bong Seok Choi, Young Mi Kim, Yun Jin Lee, Su Eun Park, Sang Ook Nam
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Clin Exp Pediatr. 2002;45(10):1284-1288. Published online October 15, 2002
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Hyperekplexia or startle disease is a hereditary neurological disorder characterized by an abnormally
exaggerated startle response to tactile, auditory and visual stimuli, together with a global
muscular hypertonia and hyperactive tendon reflexes. This disease is a rare, genetically determined
disorder, with an autosomal dominant inheritance with variable expression, first described
by Suhren, et al. We report two cases of familial hyperekplexia, who developed hypertonia... |
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- Original Article
- The Relationship between Change of Cardiac Function and Systemic Oxygen Consumption according to the Dose of Dopamine in the Rabbit
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Hee Ju Park, Seok Ho Yoon, Bong Seok Choi, Jung Hwoi Cho, Ku Tae Kim, Sun Young K, Sang Ook Nam, Bok Luel Lee
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Clin Exp Pediatr. 2001;44(2):177-184. Published online February 15, 2001
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Purpose : We'd like to know the relationship between the changes of cardiac function and systemic O2 consumption according to the increasing dose of dopamine.
Methods : Ten rabbits(from 2kg to 2.8kg) were used in this experiment. Anesthesia was induced with intraperitoneal pentobarbital sodium(35mg/kg) and tracheostomy was done. It was maintained by ventilation with a mixture of 1-3% halothane and 67-69%... |
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